To this end, adult mice were administered either kefir (UK4) or a milk control for three weeks as treatment lead-in, after which they were assessed for their behavioural phenotype using a battery of tests. ![]() As such, we hypothesized that kefir could ameliorate behavioural deficits in a mouse model relevant to ASD the BTBR T + Itpr3 tf/J mouse strain. ![]() A novel modulator of the gut microbiome, the traditionally fermented milk drink kefir, has recently been shown to modulate the microbiota and decrease repetitive behaviour, one of the hallmarks of ASD, in mice. The gut microbiome has emerged as a potential therapeutic target in ASD. There is a great need for more effective strategies to improve quality of life in ASD subjects. Autism spectrum disorder (ASD) is one of the most severe developmental disorders, affecting on average 1 in 150 children worldwide.
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